Sprinter is based on a van sold in Europe as a Mercedes-Benz and is intended for commercial use. Cargo and Passenger versions are offered. Both have two front doors, a sliding side door on the passenger side, and swing-out rear doors. The 2007 Dodge Sprinter is available in standard or high roof form and comes with either a 144 or 170 inch wheelbase. The high roof adds 9 inches of interior room.

Both available engines come from Mercedes-Benz. Available are a conventional 3.5-liter V6 and a 3.0-liter turbodiesel V6. Both mate to a 5-speed automatic transmission. Available safety equipment includes dual front airbags, ABS, and an antiskid system. Cargo models seat two on front buckets. Passenger models provide seating for up to 10, including the driver.