Porsche adds a more powerful turbocharged model to its SUV lineup for 2006. Cayenne shares a basic design with the Volkswagen Touareg, but differs in styling and engine choices. The base Cayenne has a 247-hp V6, the S model a 340-hp V8, the Turbo version a 450-hp turbocharged V8. Added during the 2006 model year, the Turbo S has a 520-hp turbocharged V8. The V6 comes with a 6-speed manual transmission or a 6-speed automatic, the V8s with the automatic only. Cayennes have all-wheel drive with low-range gearing and locking center differential. An off-road option includes a locking rear differential. Standard on Turbos and optional on the others is a load-leveling suspension that allows driver adjustment for firmness and ride height. Turbo S models have specific suspension tuning and larger brakes.

Front side airbags, curtain side airbags, ABS, and traction/antiskid control are standard. A navigation system is optional. Also available are heated steering wheel and seats, and front and rear obstacle detection. Ability to heat and cool the interior with the ignition off is newly available.