Addition of a hybrid model headlines 2006 for the best-selling Lexus. RX is the upscale cousin of the Highlander SUV from parent company Toyota. Both are based on the Toyota Camry sedan platform, but the RX seats five passengers vs. Highlander's seven. The RX 330 model has a 223-hp V6 engine and 5-speed automatic transmission. The gas/electric hybrid is the RX 400h. It teams the V6 with battery-powered electric motors for a net 268 hp. It uses a continuously variable automatic transmission (CVT) providing near-infinite drive ratios. Like other Toyota hybrids, the RX 400h automatically runs on one or both of its power sources to balance acceleration and fuel economy. No plug-in charging is required.

Both RX models are available with front-wheel drive or all-wheel drive that lacks low-range gearing. Both include ABS and antiskid/traction control. Also standard are a driver knee airbag, front side airbags, and head-protecting curtain side airbags with rollover deployment. The 400h has sport-suspension tuning and features that are options for the 330, including steering-linked xenon headlamps, leather upholstery, and power tilt/telescope steering column. Options exclusive to the 330 include adaptive cruise control, a multipanel sunroof, and self-leveling air suspension with driver-selectable height settings. Rear DVD entertainment and a navigation system with voice activation and rearview camera are available for all RXs.